INT33171

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Context Info
Confidence 0.39
First Reported 1985
Last Reported 1985
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adra2a) plasma membrane (Adra2a) cytoplasm (Adra2a)
signal transducer activity (Adra2a)
Adra2a (Mus musculus)
Pain Link Frequency Relevance Heat
noradrenaline 3 99.98 Very High Very High Very High
antidepressant 4 98.56 Very High Very High Very High
Clonidine 3 84.96 Quite High
antagonist 1 64.16 Quite High
Serotonin 2 51.04 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mianserin is a tetracyclic antidepressant whose postulated mechanism of action involves release of noradrenaline mediated via cortical alpha 2-adrenergic autoreceptor blockade.
Positive_regulation (mediated) of Negative_regulation (blockade) of 2-adrenergic associated with antidepressant and noradrenaline
1) Confidence 0.39 Published 1985 Journal Acta Psychiatr Scand Suppl Section Abstract Doc Link 2996305 Disease Relevance 0 Pain Relevance 0.40

General Comments

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