INT331873

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Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F8) oxidoreductase activity (F8) extracellular region (F8)
endoplasmic reticulum (Mest) cell adhesion (F8) plasma membrane (F8)
F8 (Homo sapiens)
Mest (Mus musculus)
Pain Link Frequency Relevance Heat
cva 3 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coagulation Disorder 49 7.92 Low Low
Hemorrhage 20 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Factor Viii Deficiency 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Thrombosis 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FVIII binds PEGLip specifically and with high affinity (two binding sites, KD of 4.5 and 1.9 nM), but this interaction does not alter FVIII activity, as shown by maintenance of full activity after formulation.45,46 The association of FVIII with PEGLip does not affect the FVIII protein’s structure.
Neg (not) Regulation (affect) of FVIII Binding (association) of PEG
1) Confidence 0.46 Published 2010 Journal Int J Nanomedicine Section Body Doc Link PMC2939703 Disease Relevance 0 Pain Relevance 0

General Comments

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