INT332136

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0

nucleoplasm (HJURP) chromosome segregation (HJURP) histone binding (HJURP) transferase activity, transferring glycosyl groups (POGLUT1) endoplasmic reticulum (POGLUT1) cytoplasm (HJURP)

Anatomy Link Frequency embryos 1 POGLUT1 (Homo sapiens) HJURP (Homo sapiens)

Pain Link Frequency Relevance Heat Central nervous system 4 5.00 dexamethasone 3 5.00 Spinal cord 2 5.00 addiction 1 5.00 melanocortin 1 receptor 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 3 56.32 Microphthalmia 11 5.00 Death 11 5.00 Skin Cancer 7 5.00 Apoptosis 5 5.00 Toxicity 4 5.00 Fibromyalgia 2 5.00 Disease 2 5.00 Trismus 2 5.00 Hypopigmentation 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The number of cells expressing dct was most clearly and most consistently reduced in tfap2a/e doubly-deficient embryos, i.e., by approximately 47% relative to the number in tfap2a mutant embryos (Figure 5A-5D, and 5M).

relative Negative_regulation (reduced) of expressing in embryos

1) Confidence 0.00 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2940735 Disease Relevance 0.06 Pain Relevance 0

General Comments

This test has worked.