INT332245

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Stat6) extracellular space (Pdgfa) extracellular region (Pdgfa)
nucleus (Stat6) DNA binding (Stat6) cytoplasm (Stat6)
Anatomy Link Frequency
mesenchymal cell 1
Pdgfa (Mus musculus)
Stat6 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 13 100.00 Very High Very High Very High
fibrosis 101 78.40 Quite High
chemokine 6 7.96 Low Low
Inflammation 14 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 16 99.08 Very High Very High Very High
Respiratory Distress 1 94.04 High High
Lung Injury 7 91.20 High High
Hyperoxia 1 89.36 High High
Asthma 11 80.32 Quite High
Fibrosis 58 78.40 Quite High
Airway Remodeling 3 75.04 Quite High
Pulmonary Fibrosis 68 74.92 Quite High
Eosinophilia 2 72.72 Quite High
Metaplasia 2 70.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
STAT-6 is activated by Th2 cytokines such as IL-13 and IL-4, but not by polypeptide growth factors such as PDGF and EGF that mediate mesenchymal cell survival.
PDGF Positive_regulation (activated) of STAT-6 in mesenchymal cell associated with cytokine
1) Confidence 0.07 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2940818 Disease Relevance 1.22 Pain Relevance 0.19

General Comments

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