INT332268

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cndp2) peptidase activity (Cndp2) plasma membrane (Tenc1)
cytoplasm (Cndp2)
Cndp2 (Mus musculus)
Tenc1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 4 5.04 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Enkephalin 1 5.00 Very Low Very Low Very Low
bradykinin 1 5.00 Very Low Very Low Very Low
substance P 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 22 96.56 Very High Very High Very High
Weight Gain 3 74.60 Quite High
Cancer 15 42.48 Quite Low
Appetite Loss 9 42.00 Quite Low
Obesity 42 36.56 Quite Low
Targeted Disruption 13 28.12 Quite Low
Pancreatic Cancer 3 23.36 Low Low
Sprains And Strains 1 21.80 Low Low
Impaired Glucose Tolerance 4 5.04 Very Low Very Low Very Low
Overweight 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To check for candoxatril's ability to inhibit central NEP activity, we measured the peptidase's capacity to generate a NEP-specific degradation product in organs after application of different doses of candoxatril in vivo for 14 days.
peptidase Binding (generate) of NEP
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2940827 Disease Relevance 0.17 Pain Relevance 0

General Comments

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