INT332284

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IRS1, PIK3CD) plasma membrane (IRS1, PIK3CD) cell differentiation (PIK3CD)
cytosol (IRS1) nucleus (IRS1) cytoplasm (IRS1)
IRS1 (Homo sapiens)
PIK3CD (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 55.32 Quite High
cytokine 8 34.04 Quite Low
tolerance 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metabolic Syndrome 52 81.92 Quite High
Insulin Resistance 9 74.96 Quite High
Hypertension 7 73.80 Quite High
Cardiovascular Disease 5 63.76 Quite High
Diabetes Mellitus 10 55.68 Quite High
INFLAMMATION 5 55.32 Quite High
Disease 4 26.64 Quite Low
Vascular Disease 4 15.08 Low Low
Thrombosis 7 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, activated IRS-1 modulates the phosphoinositide 3-kinase (PI3K) that in turn indirectly stimulates the activity of mTOR [19].
IRS-1 Regulation (modulates) of PI3K
1) Confidence 0.15 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2940873 Disease Relevance 0.72 Pain Relevance 0.03

General Comments

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