INT332317

Context Info Confidence 0.25 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

Golgi apparatus (Cav2) mitochondrion organization (Cav2) intracellular (Cav2) protein complex (Cav2) cytoplasm (Cav2) cytosol (Cav2)

Anatomy Link Frequency neurons 2 Cav2 (Mus musculus)

Pain Link Frequency Relevance Heat Migraine 18 50.00 Pain 18 5.00 agonist 10 5.00 depression 7 5.00 headache 7 5.00 Trigeminal ganglion neurons 5 5.00 qutenza 5 5.00 imagery 4 5.00 Neurotransmitter 3 5.00 Potency 3 5.00

Disease Link Frequency Relevance Heat Ganglion Cysts 11 50.00 Migraine With Aura 5 50.00 Pain 19 5.00 Migraine Disorders 13 5.00 Depression 7 5.00 Epilepsy 3 5.00 Targeted Disruption 3 5.00 Headache 3 5.00 Nociception 3 5.00 Neurological Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Although significant, this difference was not very large probably because the number of P2X3 receptor expressing neurons that also expressed CaV2.1 channels was less than 50% of the total population whose contribution diluted the overall change (see Fig. 3F).

Negative_regulation (number) of Gene_expression (expressed) of CaV2 in neurons

1) Confidence 0.25 Published 2010 Journal Mol Pain Section Body Doc Link PMC2940876 Disease Relevance 0 Pain Relevance 0

General Comments

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