INT332322

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Camk2a) nucleus (Myoz1) kinase activity (Camk2a)
cytoplasm (Camk2a)
Anatomy Link Frequency
neuronal 1
Myoz1 (Mus musculus)
Camk2a (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 3 82.44 Quite High
Migraine 18 50.00 Quite Low
Pain 18 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
depression 7 5.00 Very Low Very Low Very Low
headache 7 5.00 Very Low Very Low Very Low
Trigeminal ganglion neurons 5 5.00 Very Low Very Low Very Low
qutenza 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 11 50.00 Quite Low
Migraine With Aura 5 50.00 Quite Low
Pain 19 5.00 Very Low Very Low Very Low
Migraine Disorders 13 5.00 Very Low Very Low Very Low
Depression 7 5.00 Very Low Very Low Very Low
Epilepsy 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Headache 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although cell-free assays show that CaMKII can inhibit calcineurin [32], in neuronal cell lines both CaMKII and calcineurin are activated by Ca2+ influx and are necessary for Ca2+-dependent signalling pathways [33].
calcineurin Positive_regulation (necessary) of CaMKII in neuronal
1) Confidence 0.05 Published 2010 Journal Mol Pain Section Body Doc Link PMC2940876 Disease Relevance 0 Pain Relevance 0.04

General Comments

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