INT332330

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

embryo development (Cdk5) cytoplasm (Cdk5) cytosol (Cdk5)
nucleocytoplasmic transport (Cdk5) cell death (Cdk5) nucleolus (Cdk5)
Cdk5 (Mus musculus)
Pirt (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 3 63.12 Quite High
Migraine 18 50.00 Quite Low
Pain 18 42.16 Quite Low
agonist 10 5.00 Very Low Very Low Very Low
depression 7 5.00 Very Low Very Low Very Low
headache 7 5.00 Very Low Very Low Very Low
Trigeminal ganglion neurons 5 5.00 Very Low Very Low Very Low
qutenza 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 11 50.00 Quite Low
Migraine With Aura 5 50.00 Quite Low
Pain 19 42.16 Quite Low
Nociception 3 32.96 Quite Low
Migraine Disorders 13 5.00 Very Low Very Low Very Low
Depression 7 5.00 Very Low Very Low Very Low
Epilepsy 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Headache 3 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upstream of this interaction, it is, however, interesting that Cdk5 is reported to downregulate P/Q-type channels [41] since in our KI model we found evidence for gain of function of such channels together with low Cdk5 membrane expression.
Cdk5 Negative_regulation (downregulate) of channels
1) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC2940876 Disease Relevance 0 Pain Relevance 0.03

General Comments

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