INT332457

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 2
KRT19 (Homo sapiens)
Pain Link Frequency Relevance Heat
ketamine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 24 98.10 Very High Very High Very High
Hepatotoxicity 16 93.36 High High
Severe Combined Immunodeficiency 8 5.00 Very Low Very Low Very Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low
Liver Disease 6 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Organ Transplantation 2 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 2 5.00 Very Low Very Low Very Low
Salivary Gland Disease 2 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To demonstrate the specificity of the primers to detect human ALB, GS, and CK19 mRNA, we examined the mRNA in nontransplanted mice livers (G2) and in normal control mice livers (G3).
Transcription (detect) of CK19 in livers
1) Confidence 0.28 Published 2010 Journal Stem Cell Res Ther Section Body Doc Link PMC2941114 Disease Relevance 0 Pain Relevance 0
However, in the mice (G1) with radiation-mediated liver injury that received CD34+ HSCs transplantation 21 days later, RT-PCR analysis showed that human GS, CK19 and ALB mRNA were expressed (Figure 3), which meant a portion of the transplanted human stem cells had localized to the liver and had begun to express human ALB when analyzed 21 days after the liver damage.


Transcription (expressed) of CK19 in liver associated with injury and hepatotoxicity
2) Confidence 0.22 Published 2010 Journal Stem Cell Res Ther Section Body Doc Link PMC2941114 Disease Relevance 0.19 Pain Relevance 0

General Comments

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