INT332476

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Context Info
Confidence 0.65
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) transport (Trpv1) plasma membrane (Trpv1)
transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
Endocannabinoid 14 99.84 Very High Very High Very High
Pain 2 99.58 Very High Very High Very High
Paracetamol 92 92.08 High High
Antinociceptive 31 90.88 High High
antinociception 12 66.32 Quite High
Eae 6 29.76 Quite Low
withdrawal 5 8.52 Low Low
Intracerebroventricular 10 8.08 Low Low
Analgesic 13 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 2 99.58 Very High Very High Very High
Inflammatory Pain 2 29.76 Quite Low
Nociception 9 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown in vitro, AM404 interferes with several important targets and mechanisms in the pain pathways, including TRPV1, COX and the cellular uptake and degradation of endocannabinoids.
Protein_catabolism (degradation) of TRPV1 associated with endocannabinoid and pain
1) Confidence 0.65 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2941447 Disease Relevance 0.10 Pain Relevance 1.02

General Comments

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