INT332487

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (SGPP2) endoplasmic reticulum (SGPP2) protein binding, bridging (ANXA1)
cilium (ANXA1) protein complex (ANXA1) lipid metabolic process (ANXA1)
Anatomy Link Frequency
leukocytes 2
ANXA1 (Homo sapiens)
SGPP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 50.00 Quite Low
Inflammation 28 41.32 Quite Low
cINOD 5 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
acular 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 7 77.68 Quite High
INFLAMMATION 32 41.32 Quite Low
Multiple Sclerosis 1 37.80 Quite Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Bacterial Respiratory Disease 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
6) increase in SGPP2 expression in both type of cells, suggesting that AnxA1 can up-regulate SGPP2 expression not only in an artificial system (e.g. transfected HEK293 cells which over-express ALX), but also in primary human leukocytes that naturally express the receptor.


AnxA1 Regulation (regulate) of Gene_expression (expression) of SGPP2 in leukocytes
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2941452 Disease Relevance 0.08 Pain Relevance 0

General Comments

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