INT332489

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Context Info
Confidence 0.27
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (JAM3) small molecule metabolic process (SGPP2) extracellular region (JAM3)
endoplasmic reticulum (SGPP2) cell adhesion (JAM3) plasma membrane (JAM3)
Anatomy Link Frequency
immune system 1
JAM3 (Homo sapiens)
SGPP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 28 83.60 Quite High
agonist 2 50.00 Quite Low
chemokine 2 23.16 Low Low
cytokine 2 16.44 Low Low
cINOD 5 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
acular 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 32 83.60 Quite High
Multiple Sclerosis 1 80.08 Quite High
Cytomegalovirus Infection 7 78.48 Quite High
Cancer 3 26.24 Quite Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Bacterial Respiratory Disease 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We focused here on three genes: SGPP2, as it controls the trafficking of lymphocytes in the thymus and lymphoid organs [19], JAG1, which is related to T cell function and could be related to the role of AnxA1 in the adaptive immune system [13], [29], and JAM3, as previously mentioned.
JAM3 Binding (trafficking) of SGPP2 in immune system
1) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2941452 Disease Relevance 0.24 Pain Relevance 0.04

General Comments

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