INT332588

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.88
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (RAPH1) nucleus (MND1) plasma membrane (RAPH1)
cytoskeleton (RAPH1) DNA binding (MND1) cytoplasm (RAPH1)
RAPH1 (Homo sapiens)
MND1 (Homo sapiens)
Pain Link Frequency Relevance Heat
peripheral neuropathy 4 71.96 Quite High
Inflammation 2 68.64 Quite High
Spinal cord 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Action potential 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
peptic ulcer disease 2 5.00 Very Low Very Low Very Low
nud 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Motor Neuron Diseases 176 100.00 Very High Very High Very High
Lymphoproliferative Disease 16 100.00 Very High Very High Very High
Macroglobulinemia 4 92.80 High High
Malignant Neoplastic Disease 24 92.00 High High
Neurological Disease 4 87.32 High High
Paraproteinemias 16 81.64 Quite High
Lymphatic System Cancer 6 80.76 Quite High
Myeloproliferative Disorder 10 77.20 Quite High
Neuropathic Pain 10 75.76 Quite High
Peripheral Neuropathy 6 71.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When MND does occur in association with LPD, it appears to have both UMN and LMN involvement compatible with a diagnosis of ALS [8].
LPD Binding (association) of MND associated with lymphoproliferative disease and motor neuron diseases
1) Confidence 0.01 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2941760 Disease Relevance 2.21 Pain Relevance 0.03
The association between MND and LPD could be coincidental, but LPD seems to be disproportionately frequent in patients with MND compared to the population in general [5].
LPD Binding (association) of MND associated with lymphoproliferative disease and motor neuron diseases
2) Confidence 0.01 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2941760 Disease Relevance 1.68 Pain Relevance 0.04

General Comments

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