INT3326

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Context Info
Confidence 0.01
First Reported 1978
Last Reported 1982
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PRSS1) extracellular space (PRSS1) extracellular region (PRSS1)
Anatomy Link Frequency
plasma 2
PRSS1 (Homo sapiens)
ATP6AP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 2 87.60 High High
anesthesia 3 63.28 Quite High
Disease Link Frequency Relevance Heat
Hypertension 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Trypsin activates prorenin well at 4 mg/ml, when exposed for 30 min at 23 degrees, provided the subsequent PRA incubation stage is kept short, e.g. 10 vs 30 min.
Trypsin Positive_regulation (activates) of prorenin
1) Confidence 0.01 Published 1982 Journal Clin Exp Hypertens A Section Abstract Doc Link 6756692 Disease Relevance 0 Pain Relevance 0.11
In human plasma, trypsin activates "prorenin" within 1 min at 23 degrees C.
trypsin Positive_regulation (activates) of prorenin in plasma
2) Confidence 0.01 Published 1982 Journal Clin Exp Hypertens A Section Abstract Doc Link 6756692 Disease Relevance 0 Pain Relevance 0
Trypsin at near optimal concentrations also consistently activates human plasma prorenin, whether at 4, 23, or 37 degrees C indicating that cold is not an essential concomitant of tryptic activation.
Trypsin Spec (whether) Positive_regulation (activates) of prorenin in plasma
3) Confidence 0.00 Published 1978 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 709420 Disease Relevance 0 Pain Relevance 0

General Comments

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