INT332623

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Dpp4) extracellular region (Dpp4) cell adhesion (Dpp4)
Golgi apparatus (Dpp4) endoplasmic reticulum (Dpp4) plasma membrane (Dpp4)
Dpp4 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 4 96.28 Very High Very High Very High
tolerance 7 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
pruritus 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 95 95.52 Very High Very High Very High
Weight Loss 2 93.56 High High
Obesity 10 76.00 Quite High
Hypoglycemia 29 66.00 Quite High
Insulin Resistance 16 65.00 Quite High
Stress 1 61.08 Quite High
Congenital Anomalies 4 40.96 Quite Low
Hyperglycemia 11 5.00 Very Low Very Low Very Low
Atherosclerosis 10 5.00 Very Low Very Low Very Low
Heart Rate Under Development 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blocking the endogenous enzyme, DPP-4, which degrades active GLP-1, which is also effective in elevating to normal the reduced circulating GLP-1 levels that are present in T2DM.
Positive_regulation (active) of Protein_catabolism (degrades) of DPP-4 associated with diabetes mellitus
1) Confidence 0.19 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2941781 Disease Relevance 1.02 Pain Relevance 0.05

General Comments

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