INT332685

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) nucleolus (Trib3)
plasma membrane (Ros1) nucleus (Trib3) enzyme binding (Trib3)
Trib3 (Rattus norvegicus)
Ros1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 2 87.84 High High
Kinase C 10 82.08 Quite High
Bioavailability 5 75.80 Quite High
Inflammation 5 15.40 Low Low
antagonist 7 5.72 Low Low
cva 3 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 1 79.56 Quite High
Diabetes Complications 3 78.64 Quite High
Stress 15 74.16 Quite High
Diabetes Mellitus 29 70.60 Quite High
Congenital Anomalies 12 69.36 Quite High
Parkinson's Disease 1 56.64 Quite High
Uterine Fibroids 1 55.12 Quite High
Hyperglycemia 9 51.04 Quite High
Insulin Resistance 3 36.64 Quite Low
Hepatopulmonary Syndrome 1 27.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ROS activate p38 kinase, which further promotes ROS generation, forming a positive feedback loop to sustain ROS-p38 kinase signaling, which may associate with a reduction in SIRT1 protein expression.
kinase Positive_regulation (promotes) of ROS Binding (generation) of
1) Confidence 0.01 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2941789 Disease Relevance 0.74 Pain Relevance 0.12

General Comments

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