INT332700

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F12, KNG1) extracellular region (F12, KNG1) plasma membrane (F12, KNG1)
peptidase activity (F12)
F12 (Homo sapiens)
KNG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 20 100.00 Very High Very High Very High
ischemia 2 57.36 Quite High
agonist 2 31.92 Quite Low
analgesia 1 29.40 Quite Low
Pain 5 23.28 Low Low
b2 receptor 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
B1 receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 18 99.82 Very High Very High Very High
Hereditary Angioedema 35 96.28 Very High Very High Very High
Angioedema 5 95.66 Very High Very High Very High
Cirrhosis 2 71.72 Quite High
Hypertension 2 68.36 Quite High
Brain Hemorrhage 1 57.36 Quite High
Infarction 1 52.12 Quite High
Coronary Artery Disease 1 51.68 Quite High
Emergencies 5 48.88 Quite Low
Pain 4 23.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, it would be a logical choice in acquired angioedema due to C1 inhibitor deficiency, especially where large doses of C1 inhibitor would otherwise be required.23,49 It could potentially be of use in angiotensin converting enzyme (ACE) inhibitor-related swelling, and in HAE3, which in some cases at least, is associated with factor XII mutations and consequent bradykinin overproduction,50 although it has not been tested for these indications.
HAE3 Binding (associated) of bradykinin associated with pressure and volume under development, hereditary angioedema, angioedema and bradykinin
1) Confidence 0.15 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2941790 Disease Relevance 1.05 Pain Relevance 0.21

General Comments

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