INT332774

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.69
Pain Relevance 2.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (FSCN1) cell motility (FSCN1) protein binding, bridging (FSCN1)
cytoplasm (FSCN1)
FSCN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal nerve ligature 114 100.00 Very High Very High Very High
nMDA receptor 12 100.00 Very High Very High Very High
ketamine 188 99.92 Very High Very High Very High
Neuropathic pain 100 98.96 Very High Very High Very High
allodynia 58 96.32 Very High Very High Very High
Analgesic 34 88.08 High High
withdrawal 4 84.88 Quite High
analgesia 4 83.00 Quite High
antagonist 24 68.00 Quite High
spinal dorsal horn 8 57.12 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 160 98.96 Very High Very High Very High
Pain 14 32.84 Quite Low
Nervous System Injury 8 5.00 Very Low Very Low Very Low
Sleep Disorders 6 5.00 Very Low Very Low Very Low
Nociception 6 5.00 Very Low Very Low Very Low
Vomiting 4 5.00 Very Low Very Low Very Low
Anorexia 2 5.00 Very Low Very Low Very Low
Dizziness 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of ketamine on SNL-induced NMDAR phosphorylation
Positive_regulation (induced) of Phosphorylation (phosphorylation) of SNL associated with ketamine and spinal nerve ligature
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2942826 Disease Relevance 0.18 Pain Relevance 0.94
Western blot and immunohistochemistry were performed to confirm the effects of these two agents, administered individually or together, on SNL-induced NMDA receptor phosphorylation and astrocytic activation.


Positive_regulation (activation) of Phosphorylation (phosphorylation) of SNL associated with nmda receptor and spinal nerve ligature
2) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2942826 Disease Relevance 0.51 Pain Relevance 1.68

General Comments

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