INT332942

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.20 Pain Relevance 0.05

lipid binding (PPARA) nucleoplasm (PPARA) small molecule metabolic process (PPARA) nucleus (PPARA) DNA binding (PPARA) lipid metabolic process (PPARA)

PPARA (Homo sapiens) A.seq (Mus musculus)

Pain Link Frequency Relevance Heat dexamethasone 2 98.76 Inflammation 20 5.00 agonist 8 5.00 cINOD 2 5.00

Disease Link Frequency Relevance Heat Obesity 102 89.16 Pathologic Processes 4 27.40 Disease 46 5.00 Diabetes Mellitus 30 5.00 INFLAMMATION 22 5.00 Insulin Resistance 14 5.00 Atherosclerosis 8 5.00 Hyperandrogenism 8 5.00 Metabolic Syndrome 6 5.00 Stress 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This genome-wide ChIP-Seq analysis allowed to confirm the binding of PPAR?

PPAR Binding (binding) of ChIP-Seq

1) Confidence 0.01 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943117 Disease Relevance 0.20 Pain Relevance 0

We firmly believe that combining a sequencing-based ChIP assay to high-throughput transcriptome analysis by RNA-Seq on NGS platforms, above all for inducible transcription factors (and PPAR?

PPAR Binding (combining) of RNA-Seq

2) Confidence 0.01 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943117 Disease Relevance 0 Pain Relevance 0.05

General Comments

This test has worked.