INT332960

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.99
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Atp6v1e1) transport (Atp6v1e1) mitochondrion (Atp6v1e1)
DNA binding (Ppara) lipid metabolic process (Ppara) cytoplasm (Atp6v1e1)
Anatomy Link Frequency
body 1
Atp6v1e1 (Mus musculus)
Ppara (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 8 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 266 99.86 Very High Very High Very High
Body Weight 142 99.60 Very High Very High Very High
Metabolic Disorder 18 78.88 Quite High
Diabetes Mellitus 16 76.56 Quite High
Increased Venous Pressure Under Development 6 75.20 Quite High
Hypertension 6 73.52 Quite High
Appetite Loss 4 30.88 Quite Low
Disorder Of Lipid Metabolism 24 8.60 Low Low
Cardiovascular Disease 16 5.00 Very Low Very Low Very Low
Insulin Resistance 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that E2 inhibition of PPAR?
E2 Negative_regulation (inhibition) of PPAR
1) Confidence 0.18 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0 Pain Relevance 0
Although E2 alone decreases body weight gain and WAT mass, E2 may impair PPAR?
E2 Negative_regulation (impair) of PPAR in body associated with body weight and obesity
2) Confidence 0.13 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0.99 Pain Relevance 0

General Comments

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