INT33317

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Context Info
Confidence 0.31
First Reported 1985
Last Reported 1985
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RIPK1) signal transduction (RIPK1) mitochondrion (RIPK1)
plasma membrane (RIPK1) cytoplasm (RIPK1)
RIPK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 99.08 Very High Very High Very High
Analgesic 3 98.80 Very High Very High Very High
Enkephalin 2 97.92 Very High Very High Very High
Morphine 1 97.44 Very High Very High Very High
opiate 1 80.48 Quite High
analgesia 1 68.56 Quite High
Disease Link Frequency Relevance Heat
Hypotension 2 53.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The new inhibitors were compared with known renin inhibitors (RIP, pepstatin, H-77) and opioid analgesic agents (Met-enkephalin, morphine), with the following results: The new inhibitors were active against human renin (IC50 approximately 10-5M), but inactive against rat renin and pepsin.
Negative_regulation (inhibitors) of RIP associated with analgesic, enkephalin, opioid and morphine
1) Confidence 0.31 Published 1985 Journal Clin Exp Hypertens A Section Abstract Doc Link 3000656 Disease Relevance 0.05 Pain Relevance 0.67

General Comments

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