INT333258

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bak1) endoplasmic reticulum (Bak1) intracellular (Bak1)
cytosol (Bak1) cell proliferation (Bak1) extracellular space (Cxcl12)
Cxcl12 (Mus musculus)
Bak1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 21 50.00 Quite Low
imagery 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 35 94.16 High High
Repression 5 91.68 High High
Colon Cancer 25 85.44 High High
Carcinoma 25 82.84 Quite High
Apoptosis 46 63.08 Quite High
Metastasis 25 5.00 Very Low Very Low Very Low
Cancer 18 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Breast Cancer 4 5.00 Very Low Very Low Very Low
Bordatella Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Together these results suggest constitutive CXCL12 production during anchorage-independent growth induces anoikis via Bak upregulation resulting in subsequent release of cytochrome c.


Gene_expression (production) of CXCL12 Positive_regulation (induces) of Positive_regulation (upregulation) of Bak
1) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943927 Disease Relevance 0.55 Pain Relevance 0

General Comments

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