INT333268

Context Info Confidence 0.38 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0.05

extracellular space (Ccl20) signal transduction (Tlr4) extracellular region (Ccl20) plasma membrane (Tlr4) intracellular (Tlr4) cytoplasm (Tlr4)

Anatomy Link Frequency epithelial cells 2 Tlr4 (Mus musculus) Ccl20 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammatory response 9 98.80 Inflammation 16 48.24 Inflammatory mediators 11 44.60 chemokine 9 30.32 cytokine 5 28.68 ketamine 1 5.00 Pain 1 5.00 halothane 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 32 98.60 Chlamydia Infection 24 61.20 Sprains And Strains 1 47.56 Peritonitis 2 6.24 Infection 5 5.00 Bacterial Infection 3 5.00 Reprotox - General 3 3 5.00 Disease 2 5.00 Pain 1 5.00 Reprotox - General 1 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Most endometrial cell inflammatory responses to the different sources of LPS were similar, although the LPS from E. coli serotype O73:H16 increased CCL20 production from stromal and epithelial cells compared with the other sources of LPS (Fig. 5C,G; Dunnett's pairwise multiple comparison t test, P<0.05).

LPS Positive_regulation (increased) of Gene_expression (production) of CCL20 in epithelial cells associated with inflammatory response

1) Confidence 0.38 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943929 Disease Relevance 0.16 Pain Relevance 0.05

General Comments

This test has worked.