INT333288

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.62
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Zic2) nucleus (Zic2) DNA binding (Zic2)
Anatomy Link Frequency
retina 6
neurons 2
Zic2 (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 132 97.12 Very High Very High Very High
fluoxetine 40 64.32 Quite High
Raphe 16 5.00 Very Low Very Low Very Low
monoamine 8 5.00 Very Low Very Low Very Low
primary somatosensory cortex 4 5.00 Very Low Very Low Very Low
Thalamus 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Handedness 48 95.44 Very High Very High Very High
Vibrio Infection 4 91.64 High High
Adhesions 4 42.36 Quite Low
Ganglion Cysts 12 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with Zic2 expression, Sert mRNA was detected in the VT retina at this age.
Regulation (Consistent) of Gene_expression (expression) of Zic2 in retina
1) Confidence 0.45 Published 2010 Journal EMBO J Section Body Doc Link PMC2944059 Disease Relevance 0 Pain Relevance 0.03
As reported previously, ectopic expression of Zic2/EGFP in the centre of the retina caused ?
Regulation (ectopic) of Gene_expression (expression) of Zic2 in retina
2) Confidence 0.45 Published 2010 Journal EMBO J Section Body Doc Link PMC2944059 Disease Relevance 0.24 Pain Relevance 0
As reported previously, ectopic expression of Zic2/EGFP in the centre of the retina caused ?
Regulation (centre) of Gene_expression (expression) of Zic2 in retina
3) Confidence 0.45 Published 2010 Journal EMBO J Section Body Doc Link PMC2944059 Disease Relevance 0.24 Pain Relevance 0
It seems more plausible that ectopic expression of Zic2 in central retina affects the refinement process of these neurons because the relative levels of serotonin they sense are not perfectly balanced.
Regulation (affects) of Gene_expression (expression) of Zic2 in neurons associated with serotonin
4) Confidence 0.45 Published 2010 Journal EMBO J Section Body Doc Link PMC2944059 Disease Relevance 0.14 Pain Relevance 0.11

General Comments

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