INT333446

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ATM, CHEK1) cytoplasm (ATM, CHEK1) nucleus (ATM, CHEK1)
DNA binding (ATM) cytosol (CHEK1) signal transduction (ATM)
ATM (Homo sapiens)
CHEK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
long-term potentiation 14 5.00 Very Low Very Low Very Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These two relationships are illustrated in Figure 7 where we see ATM activating CHK1, CHK2 and MDM2 inhibiting p53.
ATM Positive_regulation (activating) of CHK1
1) Confidence 0.20 Published 2010 Journal BMC Bioinformatics Section Body Doc Link PMC2944280 Disease Relevance 0 Pain Relevance 0
The other component depiciting gene-gene relationships refer to relationships (eg MDM2 inhibits P53, ATM activates CHK1) in the pathway diagram.
ATM Positive_regulation (activates) of CHK1
2) Confidence 0.13 Published 2010 Journal BMC Bioinformatics Section Body Doc Link PMC2944280 Disease Relevance 0 Pain Relevance 0

General Comments

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