INT333510

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (STON1, GPI) isomerase activity (GPI) small molecule metabolic process (GPI)
carbohydrate metabolic process (GPI) cytosol (GPI) extracellular space (GPI)
STON1 (Homo sapiens)
GPI (Homo sapiens)
Pain Link Frequency Relevance Heat
deep brain stimulation 57 93.68 High High
Thalamus 31 55.28 Quite High
depression 1 50.88 Quite High
neurotransmitter 3 42.32 Quite Low
dopamine 8 36.28 Quite Low
action potential 6 13.84 Low Low
substantia nigra 4 5.00 Very Low Very Low Very Low
Palliative 2 5.00 Very Low Very Low Very Low
Imagery 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 70 99.88 Very High Very High Very High
Convulsion 2 79.48 Quite High
Depression 1 50.88 Quite High
Parkinson's Disease 26 43.68 Quite Low
Tremor 10 5.00 Very Low Very Low Very Low
Hypokinesia 5 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low
Burns 2 5.00 Very Low Very Low Very Low
Brain Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have evidence of excessive activity of the GPi in Parkinson’s disease, but stimulation of the STN should further increase the GPi activity.
Positive_regulation (stimulation) of STN Positive_regulation (increase) of GPi associated with disease
1) Confidence 0.10 Published 2010 Journal Philosophical transactions. Series A, Mathematical, physical, and engineering sciences Section Body Doc Link PMC2944387 Disease Relevance 0.38 Pain Relevance 0.19

General Comments

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