INT333549

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.20
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CTLA4, PDCD1) signal transduction (PDCD1) Golgi apparatus (CTLA4)
signal transducer activity (PDCD1)
CTLA4 (Homo sapiens)
PDCD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 7 79.92 Quite High
sNRI 4 76.16 Quite High
depression 2 72.40 Quite High
rheumatoid arthritis 1 69.48 Quite High
Lasting pain 2 48.80 Quite Low
antidepressant 1 46.80 Quite Low
sSRI 3 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 39 98.20 Very High Very High Very High
Depression 2 72.40 Quite High
Rheumatoid Arthritis 1 69.48 Quite High
Diabetes Mellitus 5 68.48 Quite High
Autoimmune Disease 1 67.64 Quite High
Apoptosis 4 61.44 Quite High
Pain 2 48.80 Quite Low
Thyroid Disease 2 37.32 Quite Low
Graves' Ophthalmopathy 1 26.92 Quite Low
Anxiety Disorder 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This functional association between PDCD1 and CTLA4 explains the relationship between PDCD1 and GD, and indicates that the CoPub Discovery predicted association between PDCD1 and GD was correctly identified based on biological knowledge.


CTLA4 Binding (association) of PDCD1 associated with disease
1) Confidence 0.36 Published 2010 Journal PLoS Computational Biology Section Body Doc Link PMC2944780 Disease Relevance 1.20 Pain Relevance 0.27

General Comments

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