INT333563

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PRKCA, IRF3) cytoplasm (PRKCA, IRF3) cytosol (PRKCA, IRF3)
nucleus (PRKCA, IRF3) plasma membrane (PRKCA, IRF3) mitochondrion (PRKCA)
PRKCA (Homo sapiens)
IRF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 1 27.04 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 58.00 Quite High
Urinary Tract Infection 32 5.00 Very Low Very Low Very Low
Pyelonephritis 30 5.00 Very Low Very Low Very Low
Infection 27 5.00 Very Low Very Low Very Low
Sprains And Strains 17 5.00 Very Low Very Low Very Low
Disease 15 5.00 Very Low Very Low Very Low
Abscess 7 5.00 Very Low Very Low Very Low
Bacterial Respiratory Disease 4 5.00 Very Low Very Low Very Low
Bacteriuria 4 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Given that PKC-epsilon is also essential for IRF3 activation, this pathway was examined, using the pan-PKC inhibitor Bisindolylmaleimide II.
PKC Positive_regulation (essential) of Gene_expression (activation) of IRF3
1) Confidence 0.05 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2944801 Disease Relevance 0.06 Pain Relevance 0

General Comments

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