INT333591

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF3) nucleoplasm (IRF3) plasma membrane (IRF3)
nucleus (IRF3) DNA binding (IRF3) cytoplasm (IRF3)
IRF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 1 96.04 Very High Very High Very High
chemokine 1 42.64 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 17 93.80 High High
Infection 27 77.36 Quite High
Pyelonephritis 30 67.84 Quite High
Targeted Disruption 4 65.96 Quite High
Disease 15 60.72 Quite High
Fever 3 53.52 Quite High
Urinary Tract Infection 32 52.88 Quite High
Viral Infection 2 44.36 Quite Low
Bacteriuria 4 29.60 Quite Low
Abscess 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, the IRF3 response differed after LPS+sCD14 stimulation, further suggesting that pathogen recognition and pattern recognition agonists trigger partially different signaling pathways.
Negative_regulation (differed) of Gene_expression (response) of IRF3 associated with agonist
1) Confidence 0.38 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2944801 Disease Relevance 0.53 Pain Relevance 0.05

General Comments

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