INT333616

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF3) nucleoplasm (IRF3) plasma membrane (IRF3)
nucleus (IRF3) DNA binding (IRF3) cytoplasm (IRF3)
Anatomy Link Frequency
kidney 1
IRF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 1 26.00 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urinary Tract Infection 32 99.68 Very High Very High Very High
Infection 27 94.28 High High
Fever 3 92.04 High High
Renal Disease 3 86.52 High High
Pyelonephritis 30 85.64 High High
Disease 15 83.04 Quite High
Bacterial Infection 2 79.36 Quite High
Disease Susceptibility 2 67.24 Quite High
Systemic Lupus Erythematosus 3 63.52 Quite High
Bacteriuria 4 32.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, IRF3 may be a new molecular target in the diagnosis of UTI susceptibility, potentially creating more precise approaches for detection and prevention of severe, recurrent kidney infection and associated debilitating morbidity.


Spec (may) Regulation (target) of IRF3 in kidney associated with infection and urinary tract infection
1) Confidence 0.24 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2944801 Disease Relevance 1.14 Pain Relevance 0

General Comments

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