INT333631

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.15 Pain Relevance 0.03

Thse (Mus musculus) IFNA1 (Homo sapiens)

Pain Link Frequency Relevance Heat chemokine 1 63.88 agonist 1 39.12 anesthesia 2 5.00 addiction 1 5.00 cytokine 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Systemic Lupus Erythematosus 3 100.00 Disease Susceptibility 2 97.04 Pyelonephritis 30 77.60 Bacterial Infection 2 72.64 Bacteriuria 4 70.48 Disease 15 64.24 Urinary Tract Infection 32 62.68 Fever 3 58.36 Renal Disease 3 58.08 Infection 27 46.52

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It was speculated that the A-C haplotype increased IRF3 transcription and that the G-T haplotype might protect against SLE by reducing type I IFN production.

haplotype Negative_regulation (reducing) of Gene_expression (production) of IFN associated with systemic lupus erythematosus

1) Confidence 0.00 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2944801 Disease Relevance 1.15 Pain Relevance 0.03

General Comments

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