INT333633

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.13
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF3) nucleoplasm (IRF3) plasma membrane (IRF3)
nucleus (IRF3) DNA binding (IRF3) cytoplasm (IRF3)
Thse (Mus musculus)
IRF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 1 66.12 Quite High
agonist 1 41.36 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 3 98.44 Very High Very High Very High
Disease Susceptibility 2 90.08 High High
Pyelonephritis 30 79.48 Quite High
Bacteriuria 4 72.72 Quite High
Bacterial Infection 2 65.68 Quite High
Urinary Tract Infection 32 64.92 Quite High
Fever 3 60.60 Quite High
Disease 15 57.28 Quite High
Renal Disease 3 51.12 Quite High
Infection 27 48.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was speculated that the A-C haplotype increased IRF3 transcription and that the G-T haplotype might protect against SLE by reducing type I IFN production.
haplotype Positive_regulation (increased) of Transcription (transcription) of IRF3 associated with systemic lupus erythematosus
1) Confidence 0.00 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2944801 Disease Relevance 1.13 Pain Relevance 0.03

General Comments

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