INT333637

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (IRF3) DNA binding (IRF3) cytoplasm (IRF3)
cytosol (IRF3) extracellular space (Smpd1) hydrolase activity, acting on glycosyl bonds (Smpd1)
Smpd1 (Mus musculus)
IRF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 95.72 Very High Very High Very High
Pseudomonas Infection 1 95.52 Very High Very High Very High
Vibrio Infection 1 92.96 High High
Urinary Tract Infection 32 84.12 Quite High
Infection 27 83.76 Quite High
Bacterial Respiratory Disease 4 57.60 Quite High
Viral Infection 2 55.12 Quite High
Pyelonephritis 30 50.24 Quite High
Sprains And Strains 17 21.52 Low Low
Bacteriuria 4 18.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study provides evidence that P-fimbriated E. coli, SMase and exogenous, free ceramide all activate the IRF3-dependent innate immune response.
SMase Positive_regulation (activate) of IRF3
1) Confidence 0.09 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2944801 Disease Relevance 0.62 Pain Relevance 0

General Comments

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