INT333693

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Context Info
Confidence 0.27
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Hr, Trp53) nucleus (Hr, Trp53) nucleoplasm (Trp53)
mitochondrion (Trp53) endoplasmic reticulum (Trp53) enzyme binding (Trp53)
Hr (Mus musculus)
Trp53 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 78 100.00 Very High Very High Very High
Targeted Disruption 29 94.40 High High
Death 8 49.76 Quite Low
Necrosis 4 46.04 Quite Low
Injury 2 43.72 Quite Low
Stress 10 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 3 5.00 Very Low Very Low Very Low
Alopecia 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overall, our studies demonstrate that Hr evokes an anti-apoptotic response by repressing expression of p53 and pro-apoptotic events regulated by p53.



Hr Negative_regulation (repressing) of Gene_expression (expression) of p53 associated with apoptosis
1) Confidence 0.27 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2944824 Disease Relevance 0.90 Pain Relevance 0

General Comments

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