INT33374

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Context Info
Confidence 0.22
First Reported 1986
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.74
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr5b) signal transducer activity (Htr5b)
Anatomy Link Frequency
neuronal 1
Htr5b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tail-flick 5 100.00 Very High Very High Very High
antagonist 5 99.42 Very High Very High Very High
Dopamine 8 99.40 Very High Very High Very High
Morphine 5 98.94 Very High Very High Very High
monoamine 4 97.66 Very High Very High Very High
narcan 4 96.06 Very High Very High Very High
antinociception 5 90.08 High High
Spinal cord 2 68.36 Quite High
Central grey 1 67.64 Quite High
Analgesic 1 64.00 Quite High
Disease Link Frequency Relevance Heat
Stress 9 99.82 Very High Very High Very High
Nociception 2 80.32 Quite High
Urological Neuroanatomy 2 67.84 Quite High
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Microinjection of the 5-HT(3) receptor antagonist LY-278,584 (12 nmol) had no effect either on the TF reflex or on the Sm 5-HT-evoked inhibition.
Neg (no) Regulation (effect) of Sm 5-HT-evoked associated with antagonist and tail-flick
1) Confidence 0.22 Published 2005 Journal Brain Res. Section Abstract Doc Link 15869749 Disease Relevance 0.28 Pain Relevance 0.97
Naloxone administration did not alter basal hormone concentrations or neuronal monoamine activity in any brain area, but did prevent all of the morphine-induced changes as well as the ether stress-induced changes in PRL, MBH neuronal 5-HT activity, and DA synthesis in the ME of prepubertal animals.
Regulation (changes) of MBH neuronal 5-HT in neuronal associated with stress, dopamine, narcan, morphine and monoamine
2) Confidence 0.04 Published 1986 Journal Endocrinology Section Abstract Doc Link 3002767 Disease Relevance 0.46 Pain Relevance 0.73
Second, it has been difficult to demonstrate acute effects of 5-HT-biotin/5-HT on actin filamentation, structure or dynamics in the culture system given the synthetic nature of the cells.
Regulation (effects) of 5-HT-biotin
3) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682564 Disease Relevance 0 Pain Relevance 0

General Comments

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