INT333743

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6ra) extracellular region (Il6ra) enzyme binding (Il6ra)
Anatomy Link Frequency
T cells 2
Il6ra (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 22 90.40 High High
Multiple sclerosis 12 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 50 90.68 High High
Central Nervous System Disease 21 90.40 High High
Autoimmune Disease 6 42.80 Quite Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Paralysis 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Bordatella Infection 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, we studied whether vitamin D3 negatively regulate the expression of IL-6R to inhibit TH17 differentiation but we did not see any significant differences in the IL-6R expression of CD4+ T cells after co-culture with IL-6, TGF-?
Spec (whether) Regulation (regulate) of Gene_expression (expression) of IL-6R in T cells
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944871 Disease Relevance 0.45 Pain Relevance 0.12

General Comments

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