INT333753

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.34
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

thd (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 98.40 Very High Very High Very High
Central nervous system 44 46.56 Quite Low
Multiple sclerosis 24 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Demyelination 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 10 98.40 Very High Very High Very High
Multiple Sclerosis 100 75.76 Quite High
Central Nervous System Disease 42 46.56 Quite Low
Autoimmune Disease 12 5.00 Very Low Very Low Very Low
Death 8 5.00 Very Low Very Low Very Low
Paralysis 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Demyelinating Disease 4 5.00 Very Low Very Low Very Low
Bordatella Infection 4 5.00 Very Low Very Low Very Low
Immunization 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mechanism of suppression of TH17 generation by 1,25(OH)2D3 is independent on STAT1
Negative_regulation (suppression) of Gene_expression (generation) of TH17
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944871 Disease Relevance 0.17 Pain Relevance 0.05
Moreover, vitamin D3 may be a “helper” in the generation of IL-10-producing cells in an inflammatory environment but the effect of IL-10 is not essential for vitamin D3's negative regulation of TH17 generation.


Negative_regulation (regulation) of Gene_expression (generation) of TH17 associated with inflammation
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944871 Disease Relevance 0.17 Pain Relevance 0.05

General Comments

This test has worked.

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