INT333758

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.60
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand1) nucleoplasm (Hand1) enzyme binding (Hand1)
DNA binding (Hand1) cytoplasm (Hand1) nucleolus (Hand1)
Anatomy Link Frequency
T cells 1
Hand1 (Mus musculus)
Eae1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 22 92.80 High High
Spinal cord 2 90.48 High High
Multiple sclerosis 12 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 50 100.00 Very High Very High Very High
Central Nervous System Disease 21 92.80 High High
Paralysis 4 86.20 High High
Disease 4 82.84 Quite High
Bordatella Infection 2 78.52 Quite High
Autoimmune Disease 6 66.88 Quite High
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since previous studies demonstrated that autoreactive T cells, especially TH1 and TH17, are essential to induce EAE, we further analyzed TH cells in EAE-induced mice.
TH1 Positive_regulation (induce) of EAE in T cells associated with multiple sclerosis
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944871 Disease Relevance 1.60 Pain Relevance 0.22

General Comments

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