INT333765

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Vdr) signal transduction (Ccr6) cell morphogenesis (Vdr)
plasma membrane (Ccr6) nucleus (Vdr) DNA binding (Vdr)
Vdr (Mus musculus)
Ccr6 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 22 96.68 Very High Very High Very High
Multiple sclerosis 12 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 50 98.20 Very High Very High Very High
Central Nervous System Disease 21 96.68 Very High Very High Very High
Autoimmune Disease 6 84.56 Quite High
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Paralysis 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Bordatella Infection 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data suggest the possibility that VDR activation modulates CCR6 expression and leads to a functional hypo-responsiveness to CCL20.
Positive_regulation (activation) of VDR Regulation (modulates) of Gene_expression (expression) of CCR6
1) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944871 Disease Relevance 0.48 Pain Relevance 0.12

General Comments

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