INT333889

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Lep, Col7a1) signal transduction (Lep) extracellular space (Lep)
cell adhesion (Col7a1) proteinaceous extracellular matrix (Col7a1) intracellular (Lep)
Anatomy Link Frequency
extracellular matrix 1
Lep (Mus musculus)
Col7a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 18 95.36 Very High Very High Very High
Osteoarthritis 108 88.60 High High
Pain 25 5.00 Very Low Very Low Very Low
cytokine 16 5.00 Very Low Very Low Very Low
Neurobehavioral 7 5.00 Very Low Very Low Very Low
withdrawal 7 5.00 Very Low Very Low Very Low
tail-flick 6 5.00 Very Low Very Low Very Low
Eae 5 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
Hyperalgesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 21 95.36 Very High Very High Very High
Osteoarthritis 86 88.60 High High
Knee Osteoarthritis 34 72.28 Quite High
Obesity 76 50.00 Quite Low
Hypertrophy 1 36.60 Quite Low
Pain 23 5.00 Very Low Very Low Very Low
Anxiety Disorder 15 5.00 Very Low Very Low Very Low
Nociception 9 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Hyperalgesia 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Leptin did not significantly affect the incorporation of [3H]proline or [35S]sulfate (Figure 6a), indicating that leptin did not alter collagen or S-GAG synthesis (major components of the extracellular matrix).
leptin Neg (not) Regulation (alter) of collagen in extracellular matrix
1) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945020 Disease Relevance 0.41 Pain Relevance 0.20

General Comments

This test has worked.

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