INT333893

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (TNF) extracellular matrix organization (TNF) cytoplasm (HDAC9)
extracellular space (TNF) signal transduction (TNF) extracellular region (TNF)
HDAC9 (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 100.00 Very High Very High Very High
Inflammation 25 91.20 High High
rheumatoid arthritis 74 87.60 High High
Osteoarthritis 36 83.64 Quite High
Arthritis 5 21.36 Low Low
cytokine 5 17.76 Low Low
methotrexate 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 30 100.00 Very High Very High Very High
Apoptosis 4 95.16 Very High Very High Very High
Cancer 8 90.48 High High
Disease 9 90.16 High High
Rheumatoid Arthritis 74 87.60 High High
Frailty 38 83.64 Quite High
Repression 1 73.08 Quite High
Necrosis 4 50.00 Quite Low
Toxicity 1 31.28 Quite Low
Arthritis 5 21.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was reported that HDAC inhibitors can also reduce the expression of inflammatory mediators, such as TNF?
Negative_regulation (inhibitors) of HDAC Negative_regulation (reduce) of Gene_expression (expression) of TNF associated with inflammatory mediators
1) Confidence 0.09 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945023 Disease Relevance 1.03 Pain Relevance 0.34

General Comments

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