INT333942

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.45
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein folding (GANAB) Golgi apparatus (GANAB) endoplasmic reticulum (GANAB)
carbohydrate metabolic process (GANAB)
GANAB (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 54 72.32 Quite High
Inflammation 16 70.64 Quite High
cytokine 16 50.92 Quite High
Pain 8 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Knee Osteoarthritis 2 72.72 Quite High
Osteoarthritis 54 71.40 Quite High
Stress 18 71.36 Quite High
INFLAMMATION 18 70.64 Quite High
Adhesions 2 50.64 Quite High
Rheumatoid Arthritis 2 41.40 Quite Low
Disease 8 27.28 Quite Low
Pain 8 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The decrease of Neutral alpha-glucosidase AB (or glucosidase II, GANAB), only caused by CS alone (Figure 2), and two other metabolism-related proteins (AK1C2 and UGDH), points also to a reduction of cellular metabolism.
Negative_regulation (decrease) of alpha-glucosidase AB
1) Confidence 0.39 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945029 Disease Relevance 0.33 Pain Relevance 0.16
Three metabolic proteins, AK1C2, GANAB and UDP-glucose 6-dehydrogenase (UGDH), were also decreased.
Negative_regulation (decreased) of GANAB
2) Confidence 0.33 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945029 Disease Relevance 0.12 Pain Relevance 0

General Comments

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