INT333952

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (GLUL) small molecule metabolic process (GLUL) lyase activity (GLUL)
Golgi apparatus (GLUL) intracellular (GLUL) ligase activity (GLUL)
GLUL (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 27 98.80 Very High Very High Very High
cytokine 8 98.66 Very High Very High Very High
Inflammation 8 98.46 Very High Very High Very High
Pain 4 91.88 High High
Arthritis 1 79.56 Quite High
cINOD 1 51.16 Quite High
Analgesic 1 49.52 Quite Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 27 98.80 Very High Very High Very High
INFLAMMATION 9 98.46 Very High Very High Very High
Pain 4 91.88 High High
Arthritis 1 79.56 Quite High
Disease 4 38.88 Quite Low
Obesity 1 35.64 Quite Low
Aging 1 34.00 Quite Low
Toxicity 1 31.92 Quite Low
Stress 9 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One possible explanation for this discrepancy may be the relative participation of inflammatory cytokines in different subpopulations; and it is also hypothesized that the effects of GS and CS are better realized in patients with more severe OA, which have greater involvement of interleukin-1beta (IL-1?)
Negative_regulation (realized) of Gene_expression (effects) of GS associated with inflammation, osteoarthritis and cytokine
1) Confidence 0.15 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945029 Disease Relevance 1.00 Pain Relevance 0.71

General Comments

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