INT33396

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Context Info
Confidence 0.16
First Reported 1985
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.36
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
pituitary 1
adrenal glands 1
Scort1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 6 99.12 Very High Very High Very High
electroacupuncture 91 97.92 Very High Very High Very High
Acupuncture 13 95.88 Very High Very High Very High
Dopamine 7 95.04 Very High Very High Very High
Inflammatory response 2 94.20 High High
Hyperalgesia 14 88.80 High High
Inflammation 23 88.12 High High
Osteoarthritis 1 79.76 Quite High
opiate 1 64.32 Quite High
Arthritis 1 56.76 Quite High
Disease Link Frequency Relevance Heat
Stress 10 99.46 Very High Very High Very High
INFLAMMATION 26 94.20 High High
Hyperalgesia 16 88.80 High High
Knee Osteoarthritis 1 79.76 Quite High
Disease 4 74.92 Quite High
Shock 1 65.20 Quite High
Arthritis 1 56.76 Quite High
Pressure And Volume Under Development 18 50.00 Quite Low
Pain 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acutely administered morphine stimulated both the synthesis and release of CRF in the hypothalamus, thereby activating the pituitary-adrenocortical system in non-stressed rats, but inhibited the stress-induced CRF synthesis and ACTH-corticosterone secretion.
Localization (secretion) of ACTH-corticosterone in pituitary associated with stress and morphine
1) Confidence 0.16 Published 1985 Journal Acta Med. Okayama Section Abstract Doc Link 3004111 Disease Relevance 0.28 Pain Relevance 0.87
Since adrenal glands secrete glucocorticoids such as cortisol in humans [13]and horses [14] and corticosterone (CORT) in rabbits [15], these studies suggest that EA may activate the adrenals to increase glucocorticoid secretion, leading to suppression of inflammatory responses.
Localization (secrete) of corticosterone in adrenal glands associated with inflammatory response and electroacupuncture
2) Confidence 0.03 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC1976320 Disease Relevance 1.07 Pain Relevance 0.85

General Comments

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