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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Il6st) extracellular space (Il6st) cellular_component (Il6st)
Il6st (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 2 100.00 Very High Very High Very High
agonist 1 99.56 Very High Very High Very High
rheumatoid arthritis 1 94.72 High High
Arthritis 51 94.08 High High
Inflammation 30 85.68 High High
IPN 1 76.56 Quite High
nociceptor 2 71.60 Quite High
c fibre 1 57.04 Quite High
cytokine 4 55.28 Quite High
Pain 25 50.00 Quite Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 1 94.72 High High
Arthritis 59 94.08 High High
INFLAMMATION 27 85.68 High High
Inflammatory Pain 1 76.56 Quite High
Necrosis 2 65.00 Quite High
Cancer 2 64.64 Quite High
Nociception 5 58.00 Quite High
Pain 22 50.00 Quite Low
Hyperalgesia 19 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While sIL-6R acts as an agonist, circulating soluble gp130 (sgp130) acts as an antagonist, because it binds IL-6/sIL-6R complexes and thus prevents transsignalling [4,5].
gp130 Binding (binds) of associated with antagonist and agonist
1) Confidence 0.08 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945031 Disease Relevance 0.90 Pain Relevance 0.65

General Comments

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