INT33400

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Context Info
Confidence 0.29
First Reported 1986
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 5.12
Pain Relevance 1.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CDS1) endoplasmic reticulum (CDS1) nucleotidyltransferase activity (CDS1)
Anatomy Link Frequency
neurons 1
brain 1
mouth 1
urethra 1
glands 1
CDS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 4 99.40 Very High Very High Very High
opiate 2 99.20 Very High Very High Very High
Clonidine 9 97.20 Very High Very High Very High
rheumatoid arthritis 6 95.56 Very High Very High Very High
Inflammation 1 95.52 Very High Very High Very High
cva 2 91.56 High High
Catecholamine 3 88.76 High High
cerebral cortex 1 86.52 High High
antagonist 2 83.68 Quite High
Myofascial pain syndrome 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Fistula 2 99.92 Very High Very High Very High
Stress Incontinence 2 99.54 Very High Very High Very High
Low Back Pain 4 99.40 Very High Very High Very High
Disease 37 98.72 Very High Very High Very High
Amputation 2 98.04 Very High Very High Very High
Chronic Disease 13 96.88 Very High Very High Very High
Hypertension 2 96.60 Very High Very High Very High
Obesity 8 96.04 Very High Very High Very High
Hyperglycemia 1 95.68 Very High Very High Very High
Rheumatoid Arthritis 6 95.56 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
glands and urethra-coetaneous fistula in CDS have been reported in other
Regulation (reported) of CDS in urethra associated with fistula and stress incontinence
1) Confidence 0.29 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581731 Disease Relevance 0.57 Pain Relevance 0.11
Preliminary attempts at purification of the extracts revealed that CDS activities from the two tissues are similar, i.e., practically insoluble in organic solvents at room temperature, not affected by either Sep-Pak C18 column or anion exchange resins but retained (along with the monovalent cations) by cation exchange resin.
Neg (not) Regulation (affected) of CDS
2) Confidence 0.27 Published 1995 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 7715736 Disease Relevance 0 Pain Relevance 0.48
The effect of CDS, an endogenous brain substance that specifically displaces bound [3H]clonidine and [3H]rauwolscine in rat brain membranes and human platelets, has been tested in isolated, field-stimulated rat vas deferens.
Regulation (effect) of CDS in brain associated with clonidine
3) Confidence 0.23 Published 1986 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 3004427 Disease Relevance 0 Pain Relevance 0.33
In the AS group there was no long-term change in the CDS but an increase of mouth opening capacity.
Neg (no) Regulation (change) of CDS in mouth associated with spinal inflammation
4) Confidence 0.23 Published 1996 Journal Acta Odontol. Scand. Section Abstract Doc Link 8669235 Disease Relevance 1.05 Pain Relevance 0.67
glands and urethra-coetaneous fistula in CDS have been reported in other
Regulation (reported) of CDS in glands associated with fistula and stress incontinence
5) Confidence 0.10 Published 2008 Journal Advances in Urology Section Body Doc Link PMC2581731 Disease Relevance 0.57 Pain Relevance 0.11
We compared the time course of responses in CDS and PDS neurons in opiate-anesthetized macaques, using a rapid pseudorandom sequence of gratings and plaids that moved in different directions.
Regulation (responses) of CDS in neurons associated with opiate
6) Confidence 0.05 Published 2005 Journal Nat. Neurosci. Section Abstract Doc Link 15657600 Disease Relevance 0 Pain Relevance 0.10
JVJ, CDS and IVJ were responsible for analysis and interpretation of data.
Regulation (responsible) of CDS
7) Confidence 0.03 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2405792 Disease Relevance 0.23 Pain Relevance 0
Adding to the problem, CDs are responsible for approximately 60% of all deaths in the region, and the leading causes of CD are hypertension, obesity, hyperglycemia, and hyperlipidemia [23].
Regulation (responsible) of CDs associated with hyperglycemia, obesity, hypertension, hyperlipidemia and chronic disease
8) Confidence 0.02 Published 2010 Journal International Journal of Environmental Research and Public Health Section Body Doc Link PMC2898047 Disease Relevance 2.70 Pain Relevance 0

General Comments

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