INT334014

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Context Info
Confidence 0.59
First Reported 2010
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 3.07
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CCR9) signal transducer activity (CCR9)
Anatomy Link Frequency
monocytes 3
macrophages 1
CCR9 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 20 99.68 Very High Very High Very High
rheumatoid arthritis 416 98.68 Very High Very High Very High
chemokine 120 80.04 Quite High
Etanercept 4 73.92 Quite High
methotrexate 8 72.96 Quite High
Leflunomide 4 71.84 Quite High
Inflammation 40 61.32 Quite High
fibrosis 4 23.44 Low Low
Crohn's disease 16 5.00 Very Low Very Low Very Low
Arthritis 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 64 98.88 Very High Very High Very High
Rheumatoid Arthritis 492 98.68 Very High Very High Very High
Adhesions 12 75.48 Quite High
Reprotox - General 1 4 74.52 Quite High
Cancer 12 72.16 Quite High
Leukemia 4 66.96 Quite High
Inflammatory Bowel Disease 4 61.88 Quite High
INFLAMMATION 32 59.52 Quite High
Hypersensitivity 8 42.88 Quite Low
Synovitis 8 35.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This cytokine elicited an up-regulation of CCR9 expression as shown by flow cytometry (P < 0.01).
Regulation (regulation) of Gene_expression (expression) of CCR9 associated with cytokine
1) Confidence 0.59 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945064 Disease Relevance 0.40 Pain Relevance 0.31
Therefore we examined the expression and function of CCR9 by monocytes and macrophages in RA.


Spec (examined) Regulation (function) of Spec (examined) Gene_expression (expression) of CCR9 in monocytes associated with rheumatoid arthritis
2) Confidence 0.44 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945064 Disease Relevance 1.25 Pain Relevance 0.50
concentrations on CCR9 expression was determined by ANOVA and then pair-wise comparisons by Dunnett's test.
Regulation (concentrations) of Gene_expression (expression) of CCR9
3) Confidence 0.26 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945064 Disease Relevance 0.17 Pain Relevance 0.05
Therefore we examined the expression and function of CCR9 by monocytes and macrophages in RA.


Spec (examined) Regulation (function) of in macrophages Spec (examined) Gene_expression (expression) of CCR9 in monocytes associated with rheumatoid arthritis
4) Confidence 0.15 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945064 Disease Relevance 1.25 Pain Relevance 0.50

General Comments

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