INT334043

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ALPP) nucleus (Cdt1) DNA binding (Cdt1)
Cdt1 (Rattus norvegicus)
ALPP (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 3 100.00 Very High Very High Very High
COX-2 inhibitor 5 18.80 Low Low
cINOD 5 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cOX1 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Postmenopausal Osteoporosis 2 94.96 High High
Osteoporosis 41 85.72 High High
Hypercalcemia 3 76.48 Quite High
Lifespan 9 63.92 Quite High
Apoptosis 15 5.60 Low Low
Body Weight 3 5.00 Very Low Very Low Very Low
Fracture Healing 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Bone Cancer 2 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The addition of NS-398 inhibitor decreased significantly the Ris-induced COX2 and b-ALP gene overexpression.



Ris Positive_regulation (induced) of Gene_expression (overexpression) of ALP associated with cox2
1) Confidence 0.08 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945066 Disease Relevance 0.39 Pain Relevance 0.05

General Comments

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