INT334150

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nqo1) oxidoreductase activity (Nqo1) cytoplasm (Nqo1)
Nqo1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 4 97.48 Very High Very High Very High
Inflammation 6 97.32 Very High Very High Very High
Neuritis 14 55.76 Quite High
intrathecal 18 5.00 Very Low Very Low Very Low
Multiple sclerosis 8 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 24 100.00 Very High Very High Very High
INFLAMMATION 6 97.32 Very High Very High Very High
Optic Neuritis 14 55.76 Quite High
Disease 14 18.04 Low Low
Targeted Disruption 1 5.60 Low Low
Recurrence 35 5.00 Very Low Very Low Very Low
Demyelinating Disease 16 5.00 Very Low Very Low Very Low
Neurological Disease 5 5.00 Very Low Very Low Very Low
Acute Disease 4 5.00 Very Low Very Low Very Low
Transverse Myelitis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In an animal model of NMO, injection of AQP4-Ab positive sera and human complement into the CSF indeed resulted in generation of NMO-like lesions in the absence of BBB disruption or pre-existing CNS inflammation [34].
Positive_regulation (resulted) of Gene_expression (generation) of NMO associated with neuromyelitis optica, inflammation and central nervous system
1) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2945323 Disease Relevance 0.41 Pain Relevance 0.20

General Comments

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